5,6-Diamino-1,3-diethyluracil → 155271-99-1

HRID 375314Notes

Reaction equation

HRID 375314 reaction equation
[NH2:1][C:2]1[C:3](=[O:14])[N:4]([CH2:12][CH3:13])[C:5](=[O:11])[N:6]([CH2:9][CH3:10])[C:7]=1[NH2:8].[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH:25]=[C:26]2[O:30][CH2:29][O:28][C:27]=12)[CH:20]=[CH:21][C:22](O)=O>>[CH2:12]([N:4]1[C:3](=[O:14])[C:2]2[NH:1][C:22](/[CH:21]=[CH:20]/[C:19]3[CH:25]=[C:26]4[O:30][CH2:29][O:28][C:27]4=[C:17]([O:16][CH3:15])[CH:18]=3)=[N:8][C:7]=2[N:6]([CH2:9][CH3:10])[C:5]1=[O:11])[CH3:13]

Participants

3

Reactant 2

HCID 45721335,6-Diamino-1,3-diethyluracilHCID 53397113HCID 53397113, compound

Product 1

HCID 6448945155271-99-1Yield 53%

Procedure

Substantially the same procedure as in Example 7 was repeated using 2.50 g (12.6 mmol) of 5,6-diamino-1,3-diethyluracil and 3.31 g (14.9 mmol) of 3-methoxy-4,5-methylenedioxycinnamic acid. Then, the resultant crude crystals were recrystallized from tetrahydrofuran/water to give 600 mg (yield 53%) of Compound 169 as a white powder.

Workup

  1. customThen, the resultant crude crystals were recrystallized from tetrahydrofuran/water

Sources & evidence

ORD record
ord-6ef2c2f28a3a41f694db3f8cba7f6af9
Source dataset
uspto-grants-1996_01
Patent number
US05484920

Reaction notes

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