HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Fluorophenyl)prop-2-enoic acid → 151539-35-4
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Fluorophenyl)prop-2-enoic acid | HCID 67977 | — |
| Reactant | 5,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedione | HCID 5098605 | — |
| Product | 151539-35-4 | HCID 6448790 | 68.1% |
Reaction Steps
Substantially the same procedure as in Reference Example 1 was repeated using 3.00 g (13.3 mmol) of 5,6-diamino-1,3-dipropyluracil and 2.43 g (14.6 mmol) of 2-fluorocinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 3.23 g (yield 68%) of Compound 42 as white needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05484920 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-e267947f1827435cae038630c1e99354 |
| Source note | uspto-grants-1996_01 |