HCID 735831, compound → 155271-54-8

HRID 375344Notes

Reaction equation

HRID 375344 reaction equation
[NH2:1][C:2]1[C:3](=[O:14])[N:4]([CH2:12][CH3:13])[C:5](=[O:11])[N:6]([CH2:9][CH3:10])[C:7]=1[NH2:8].[CH3:15][O:16][C:17]1[C:27]([O:28][CH3:29])=[CH:26][C:20]([CH:21]=[CH:22][C:23](O)=O)=[C:19]([N+:30]([O-:32])=[O:31])[CH:18]=1>>[CH3:15][O:16][C:17]1[C:27]([O:28][CH3:29])=[CH:26][C:20](/[CH:21]=[CH:22]/[C:23]2[NH:1][C:2]3[C:3](=[O:14])[N:4]([CH2:12][CH3:13])[C:5](=[O:11])[N:6]([CH2:9][CH3:10])[C:7]=3[N:8]=2)=[C:19]([N+:30]([O-:32])=[O:31])[CH:18]=1

Participants

3

Reactant 2

HCID 735831HCID 735831, compoundHCID 45721335,6-Diamino-1,3-diethyluracil

Product 1

HCID 6448900155271-54-8Yield 39%

Procedure

Substantially the same procedure as in Example 7 was repeated using 1.50 g (7.57 mmol) of 5,6-diamino-1,3-diethyluracil and 2.11 g (8.33 mmol) of 4,5-dimethoxy-2-nitrocinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane to give 1.22 g (yield 39%) of Compound 124 as orange needles.

Workup

  1. customThen, the resultant crude crystals were recrystallized from dioxane

Sources & evidence

ORD record
ord-c530392048d44c32ad4c35b75d2ff974
Source dataset
uspto-grants-1996_01
Patent number
US05484920

Reaction notes

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