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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 375353Generated: October 28, 2026

HCID 735839, compound → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3-(trifluoromethoxy)phenyl)ethenyl)-, (E)-

https://huagongshe.com/reaction/375353

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 735839HCID 735839—
Reactant5,6-Diamino-1,3-diethyluracilHCID 4572133—
Product1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3-(trifluoromethoxy)phenyl)ethenyl)-, (E)-HCID 644891860%

Reaction Steps

Substantially the same procedure as in Example 7 was repeated using 1.00 g (5.05 mmol) of 5,6-diamino-1,3-diethyluracil and 1.29 g (5.56 mmol) of 3-trifluoromethoxycinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 1.19 g (yield 60%) of Compound 142 as white needles.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05484920
Source datasetuspto-grants-1996_01
ORD IDord-9b6d66bf39c842848552324aa7f5c4b4
Source noteuspto-grants-1996_01