HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Pyrrolidinophenyl)acetic acid hydrobromide → (4aRS,7aRS)6-{[2-(1-pyrrolidinyl)phenyl]acetyl}4,4-diphenylperhydrothiopyrano[2,3-c]pyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Pyrrolidinophenyl)acetic acid hydrobromide | HCID 67745326 | — |
| Reactant | (4aRS,7aRS)4,4-diphenylperhydrothiopyrano[2,3-c]pyrrole hydrochloride | HCID 67745331 | — |
| Product | (4aRS,7aRS)6-{[2-(1-pyrrolidinyl)phenyl]acetyl}4,4-diphenylperhydrothiopyrano[2,3-c]pyrrole | HCID 67745328 | 30.9% |
Reaction Steps
By carrying out the procedure as in Example of Use 1, using 1.85 g of [2-(1-pyrrolidinyl)phenyl]acetic acid hydrobromide and 2.0 g of (4aRS,7aRS)4,4-diphenylperhydrothiopyrano[2,3-c]pyrrole hydrochloride, 0.90 g of (4aRS,7aRS)6-{[2-(1-pyrrolidinyl)phenyl]acetyl}4,4-diphenylperhydrothiopyrano[2,3-c]pyrrole is obtained in the form of white crystals; melting point 166° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05484942 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-f3f4f2325da44750b66b45e54d18e8bb |
| Source note | uspto-grants-1996_01 |