HuagongsheHuagongshe Chemistry Print Report · For research reference only
(-)-4,4-Diphenylperhydrothiopyrano[2,3-c]pyrrole 1-oxide → (1RS,4aRS,7aRS)-6-{[(3-dimethylamino-2-propoxy)phenyl]acetyl}-4,4-diphenylperhydrothiopyrano[2,3-c]pyrrole 1-oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (-)-4,4-Diphenylperhydrothiopyrano[2,3-c]pyrrole 1-oxide | HCID 18995289 | — |
| Reactant | [(3-Dimethylamino-2-propoxy)phenyl]acetic acid | HCID 53734286 | — |
| Product | (1RS,4aRS,7aRS)-6-{[(3-dimethylamino-2-propoxy)phenyl]acetyl}-4,4-diphenylperhydrothiopyrano[2,3-c]pyrrole 1-oxide | HCID 67745338 | 9.7% |
Reaction Steps
By carrying out the procedure according to that described in Example 8 below, using 1.82 g of (1RS,4aRS,7aRS)-4,4-diphenylperhydrothiopyrano[2,3-c]-pyrrole 1-oxide and 1.39 g of [(3-dimethylamino-2-propoxy)phenyl]acetic acid, 0.3 g of (1RS,4aRS,7aRS)-6-{[(3-dimethylamino-2-propoxy)phenyl]acetyl}-4,4-diphenylperhydrothiopyrano[2,3-c]pyrrole 1-oxide is obtained in the form of white crystals; melting point 150° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05484942 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-85e1bf155a3f4b379cc2630d4a69cf19 |
| Source note | uspto-grants-1996_01 |