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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 37554Generated: October 29, 2026

Methyl bromoacetate → 3-Methoxy-1-(methoxycarbonylmethyl)-3-[3-(naphth-2-ylmethoxy)phenyl]pyrrolidine

https://huagongshe.com/reaction/37554

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl bromoacetateHCID 60984—
ReactantHCID 19935823HCID 19935823—
Product3-Methoxy-1-(methoxycarbonylmethyl)-3-[3-(naphth-2-ylmethoxy)phenyl]pyrrolidineHCID 19935812—

Reaction Steps

Using an analogous procedure to that described in Example 3, 3-methoxy-3-[3-(naphth-2-ylmethoxy)phenyl]pyrrolidine was reacted with methyl bromoacetate to give 3-methoxy-1-(methoxycarbonylmethyl)-3-[3-(naphth-2-ylmethoxy)phenyl]pyrrolidine in 33Z yield, m.p. 78°-80° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05420298
Source datasetuspto-grants-1995_05
ORD IDord-8733ef879e294b09919c0b5c03032b6c
Source noteuspto-grants-1995_05