HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargyl bromide → HCID 19935825, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargyl bromide | HCID 7842 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3-[3-(4-Acetylphenylthio)phenyl]-3-methoxypyrrolidine | HCID 19935854 | — |
| Product | HCID 19935825 | HCID 19935825 | 14% |
Reaction Steps
Using an analogous procedure to that described in Example 3 except that diisopropylethylamine was used in place of potassium carbonate, 3-[3-(4-acetylphenylthio)phenyl]-3-methoxypyrrolidine was reacted with 2-propynyl bromide to give 3-[3-(4-acetylphenylthio)phenyl]-3-methoxy-1-(prop-2-ynyl)pyrrolidine as a gum in 14% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05420298 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-a72bfc29aa694c8c896f27081418a248 |
| Source note | uspto-grants-1995_05 |