1-(4-Sulfanylphenyl)ethan-1-one → HCID 19935857, compound

HRID 37557Notes

Reaction equation

HRID 37557 reaction equation
[SH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[CH:4][CH:3]=1.[CH2:11]([O:13][C:14]([N:16]1[CH2:20][CH2:19][C:18]([C:23]2[CH:28]=[CH:27][CH:26]=[C:25](I)[CH:24]=2)([O:21][CH3:22])[CH2:17]1)=[O:15])[CH3:12]>>[C:8]([C:5]1[CH:6]=[CH:7][C:2]([S:1][C:27]2[CH:28]=[C:23]([C:18]3([O:21][CH3:22])[CH2:19][CH2:20][N:16]([C:14]([O:13][CH2:11][CH3:12])=[O:15])[CH2:17]3)[CH:24]=[CH:25][CH:26]=2)=[CH:3][CH:4]=1)(=[O:10])[CH3:9]

Participants

3

Reactant 2

HCID 47131801-(4-Sulfanylphenyl)ethan-1-oneHCID 19935836HCID 19935836, compound

Product 1

HCID 19935857HCID 19935857, compoundYield 24%

Procedure

Using an analogous procedure to that described in Example 10, 4'-mercaptoacetophenone was reacted with 1-ethoxycarbonyl-3-(3-iodophenyl)-3-methoxypyrrolidine to give 3-[3-(4-acetylphenylthio)phenyl]-1-ethoxycarbonyl-3-methoxypyrrolidine as a gum in 24% yield.

Sources & evidence

ORD record
ord-90402b6bf38f49b2807ceff35658b74d
Source dataset
uspto-grants-1995_05
Patent number
US05420298

Reaction notes

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