HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-(3-Fluorophenyl)propanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-(3-Fluorophenyl)propionic acid | HCID 2737489 | — |
| Product | 3-(3-Fluorophenyl)propanoyl chloride | HCID 18993501 | — |
Reaction Steps
A solution of 3-fluorohydrocinnamic acid (28 g) in thionyl chloride (90 ml) was heated at reflux for 3 hours. 3-Fluorohydrocinnamoyl chloride (27 g) was isolated by distillation (150°-110° C. @ ca 20 mm.Hg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05486541 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-66e7a4465c454ece8d230e1ae0a91cbd |
| Source note | uspto-grants-1996_01 |