HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Azidomethyl-2-carboxyethylfuran → 5-Aminomethyl-2-carboxyethylfuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Azidomethyl-2-carboxyethylfuran | HCID 18993306 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Aminomethyl-2-carboxyethylfuran | HCID 18993174 | 98.5% |
Reaction Steps
Treatment of a solution in ethanol (50 mL) at ambient temperature of 5-azidomethyl-2-carboxyethylfuran (585 mg, 3.00 mmol), prepared as in step 3, with Raney nickel 2800 and 4 atmospheres of H2 for 24 hours, followed by filtration of the reaction mixture and concentration in vacuo gave 5-aminomethyl-2-carboxyethylfuran (0.50 g) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05486525 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-6f66f430e4d846f59b020b67e134241f |
| Source note | uspto-grants-1996_01 |