Stannous Chloride → 5-[N-(3-aminopyrid-4-yl)aminomethyl]-2-carboxyethylfuran

HRID 375638Notes

Reaction equation

[N+:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[NH:10][CH2:11][C:12]1[O:16][C:15]([CH2:17][CH2:18][C:19]([OH:21])=[O:20])=[CH:14][CH:13]=1)([O-])=O.[Sn](Cl)Cl>>[NH2:1][C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[NH:10][CH2:11][C:12]1[O:16][C:15]([CH2:17][CH2:18][C:19]([OH:21])=[O:20])=[CH:14][CH:13]=1

Participants

Reactant 2

HCID 24479Stannous Chloride

HCID 189930825-[N-(3-Nitropyrid-4-yl)aminomethyl]-2-carboxyethylfuran

Product 1

HCID 189931725-[N-(3-aminopyrid-4-yl)aminomethyl]-2-carboxyethylfuran

Procedure

The desired compound was prepared by reduction of 5-[N-(3-nitropyrid-4-yl)aminomethyl]-2-carboxyethylfuran, prepared as in step 5, with tin(II) chloride.

Sources & evidence

ORD record: ord-d4ba829f3a3a4915bf565e391ee8ced4
Source dataset: uspto-grants-1996_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05486525

Reaction notes

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