HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → m-Diethyl-aminophenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 2-Bromophenol | HCID 7244 | — |
| Reactant | Lithium diethylamide | HCID 11137085 | — |
| Product | m-Diethyl-aminophenol | HCID 69344032 | 15% |
Reaction Steps
Amer. Chem. Soc., 74 (1952), 3027-29, discloses that the treatment of o-bromophenol with twice the molar amount of lithium diethylamide in boiling diethyl ether gives rise to m-diethyl-aminophenol. However, the process described there is completely unsuitable for an industrial synthesis, since m-diethylaminophenol is formed only in a yield of 15%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05486609 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-83a89c98682c4f9eb7fc4b16ecc6391c |
| Source note | uspto-grants-1996_01 |