化工社化工社 化学情報印刷レポート · 研究参考用
Phosgene → N,N-dimethyl-2-chloro-5-isocyanatobenzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phosgene | HCID 6371 | — |
| 反応物 | 5-amino-2-chloro-N,N-dimethylbenzene-1-sulfonamide | HCID 3613938 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | N,N-dimethyl-2-chloro-5-isocyanatobenzenesulfonamide | HCID 18993674 | — |
反応手順
50 g of N,N-dimethyl-2-chloro-5-aminobenzenesulfonamide (Example A-3 above) was treated with an excess of phosgene in ethyl acetate as is generally described in "Organic Functional Group Preparations" by S. R. Sandler and W. Karo on pages 364-365 (Academic Press, N.Y., 1983) (preparation of organic isocyanates), which disclosure is herein incorporated by reference. 48 g of the title compound was isolated as a tan solid with a melting point of 82°-85° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05486610 |
| 出典データセット | uspto-grants-1996_01 |
| ORD ID | ord-f23b77868c744b8897d1fa549b920425 |
| 出典メモ | uspto-grants-1996_01 |