反应详情

51 g of 2-(1-chloro-2,2,2-trifluoroethyl)-2-trifluoromethyl-1,3-benzodioxole from Example 2 or 17 were dissolved in 300 ml of carbon tetrachloride, and 0.5 g of anhydrous FeCl3 was added. 32 g of bromine were then added and the mixture was stirred for 3 hours under reflux. After cooling, it was washed with 10% NaHSO3 solution, dried over MgSO4 and distilled. The yield was 49 g (63% of theory) and the boiling point was 94°-98° C. at 8 mbar.

1. temperatureunder reflux
2. temperatureAfter cooling
3. washit was washed with 10% NaHSO3 solution
4. dry with materialdried over MgSO4
5. distillationdistilled