HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 4-[5-[4-(aminoiminomethyl)phenoxy]pentoxy]-3-methoxy-N,N-bis(1-methylethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-[5-[4-(aminoiminomethyl)phenoxy]pentoxy]-3-methoxy-N,N-bis(1-methylethyl)benzamide monohydrochloride | HCID 67744755 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[5-[4-(aminoiminomethyl)phenoxy]pentoxy]-3-methoxy-N,N-bis(1-methylethyl)benzamide | HCID 183800 | — |
Reaction Steps
Amberlite IRA-400 (OH) ion-exchange resin (55.5 g) is added in one portion to a stirred ethanol (120 mL)/methanol (30 mL) solution of 4-[5-[4-(aminoiminomethyl)phenoxy]pentyloxy]-3-methoxy-N,N-bis(1-methylethyl)benzamide monohydrochloride (20 g). After stirring for 20 hours, the resin is removed by filtration. The mother liquor is concentrated at reduced pressure to afford 4-[5-[4-(aminoiminomethyl)phenoxy]pentyloxy]-3-methoxy-N,N-bis(1-methylethyl)benzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05488160 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-4e7f40fc48484a56a9fff2817e17f1f8 |
| Source note | uspto-grants-1996_01 |