Isobutylene → t-Butyl 4-(p-fluorophenyl)butyrate

HRID 376093Notes

Reaction equation

HRID 376093 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])=[CH:4][CH:3]=1.[CH3:14][C:15](=[CH2:17])[CH3:16]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][CH2:10][C:11]([O:13][C:15]([CH3:17])([CH3:16])[CH3:14])=[O:12])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 8255IsobutyleneHCID 685244-(p-Fluorophenyl)butyric acid

Product 1

HCID 15342049t-Butyl 4-(p-fluorophenyl)butyrate

Procedure

In Scheme A, step 1, 4-(p-fluorophenyl)butyric acid is contacted with isobutylene to give t-butyl 4-(p-fluorophenyl)butyrate.

Sources & evidence

ORD record
ord-c0cea804a2904f45baecae02ac6c6662
Source dataset
uspto-grants-1996_01
Patent number
US05488188

Reaction notes

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