HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylglutaric anhydride → 4-[N-{(1RS,2RS)-2-(4-biphenylyl)-1-methyl-3-(2-naphthyl)propyl}carbamoyl]-3-methylbutanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylglutaric anhydride | HCID 77828 | — |
| Reactant | (1RS,2RS)-2-(4-biphenylyl)-1-methyl-3-(2-naphthyl)propylamine | HCID 19073559 | — |
| Product | 4-[N-{(1RS,2RS)-2-(4-biphenylyl)-1-methyl-3-(2-naphthyl)propyl}carbamoyl]-3-methylbutanoic acid | HCID 19073776 | — |
Reaction Steps
Compounds of Examples 57 to 65 were prepared in the same manner as in Example 56 except that (1RS, 2RS)-2-(4-biphenylyl)-1-methyl-3-(2-naphthyl)propylamine and/or 3-methylglutaric anhydride used as the starting materials in the above reaction were changed to the corresponding amine compounds and/or acid anhydrides.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05488149 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-f997a304720242e9ad974354c42556cb |
| Source note | uspto-grants-1996_01 |