(Cyanomethyl)triphenylphosphonium chloride → 5'-(2-Cyanovinyl)-5-methoxy-1,3,3-trimethylspiro-[indoline-2,3'-[3H]-naphtho[2,1-b][1,4]oxazine]

HRID 376212Notes

Reaction equation

HRID 376212 reaction equation
[CH:1]([C:3]1[C:12]2[O:13][C:14]3([C:24]([CH3:26])([CH3:25])[C:23]4[C:18](=[CH:19][CH:20]=[C:21]([O:27][CH3:28])[CH:22]=4)[N:17]3[CH3:29])[CH:15]=[N:16][C:11]=2[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1)=O.[Cl-].[C:31]([CH2:33][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)#[N:32]>>[C:31]([CH:33]=[CH:1][C:3]1[C:12]2[O:13][C:14]3([C:24]([CH3:25])([CH3:26])[C:23]4[C:18](=[CH:19][CH:20]=[C:21]([O:27][CH3:28])[CH:22]=4)[N:17]3[CH3:29])[CH:15]=[N:16][C:11]=2[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1)#[N:32]

Participants

3

Reactant 2

HCID 197040(Cyanomethyl)triphenylphosphonium chlorideHCID 158602975'-Formyl-5-methoxy-1,3,3-trimethylspiro[indoline-2,3'-[3H]-naphtho[2,1-b][1,4]oxazine]

Product 1

HCID 542221615'-(2-Cyanovinyl)-5-methoxy-1,3,3-trimethylspiro-[indoline-2,3'-[3H]-naphtho[2,1-b][1,4]oxazine]

Procedure

This compound is prepared according to the method employed for Example 4, from 0.39 g (1 mmol) of the compound of Example 2 and 0.34 g (1 mmol) of cyanomethyltriphenylphosphonium chloride.

Workup

  1. customThis compound is prepared

Sources & evidence

ORD record
ord-5d0305a2721849bc9d168498aaa5437f
Source dataset
uspto-grants-2000_02
Patent number
US06019914

Reaction notes

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