HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → 5'-(2-Formylvinyl)-1,3,3-trimethylspiro[indoline-2,3'-[3H]-naphtho [2,1-b][1,4]oxazine]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | (Triphenylphosphoranylidene)acetaldehyde | HCID 75051 | — |
| Reactant | 5'-Formyl-1,3,3-trimethylspiro[indoline-2,3'-[3H]-naphtho[2,1-b][1,4]oxazine] | HCID 15305689 | — |
| Product | 5'-(2-Formylvinyl)-1,3,3-trimethylspiro[indoline-2,3'-[3H]-naphtho [2,1-b][1,4]oxazine] | HCID 54399125 | — |
Reaction Steps
A solution of 0.36 g (1 mmol) of the compound of Example 1 and of 0.30 g (1 mmol) of (triphenylphosphoranylidene)acetaldehyde in 10 ml of toluene is heated to reflux for 24 hours. The solvent is then evaporated off and the mixture purified on a silica column (70/30 pentane/ether eluent).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06019914 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-e21c2f9b8ccb41b1b8d1d3002635d1c9 |
| Source note | uspto-grants-2000_02 |