Methyl morpholine oxide → HCID 9829637, compound

Participants

Reaction Steps

Tetra-n-propylammonium perruthenate (50 mg) was added to a stirred solution of the title compound of Example 2 (0.15 g) and 4-methylmorpholine N-oxide (50 mg) in acetonitrile (5 ml) containing powdered 4 Å molecular sieves. The reaction mixture was stirred at room temperature for 24 hours and then evaporated under reduced pressure. Purification of the residue by column chromatography on silica gel, using dichloromethane as eluant, followed by chromatographic reprocessing, using hexane and then a mixture of hexane: ethyl acetate (19:1) as eluants, gave the title compound as a colourless oil. δ (CDCl3): 1.83 (t,1H), 2.20 (dd,1H), 3.24 (dd,1H), 7.44 (s,1H), 7.79 (s,2H). IR (thin film): νmax 1722.9 cm-1.

Provenance & Evidence