HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 7-Chloro-3-diethylamino-2-(2-methylphenyl)imidazo[2,1-a]isoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | HCID 15462240 | HCID 15462240 | — |
| Reactant | 3-Amino-7-chloro-2-(2-methylphenyl)imidazo[2,1-a]isoquinoline | HCID 18691183 | — |
| Product | 7-Chloro-3-diethylamino-2-(2-methylphenyl)imidazo[2,1-a]isoquinoline | HCID 15462575 | — |
| Product | 7-Chloro-3-ethylamino-2-(2-methylphenyl)imidazo[2,1-a]isoquinoline | HCID 18691152 | — |
Reaction Steps
Example 10 was repeated except that 3-amino-7-chloro-2-(2-methylphenyl)imidazo[2,1-a]isoquinoline (Compound 5) and ethyl iodide were used in place of 3-amino-2-(2-methylphenyl)imidazo[2,1-a]isoquinoline and allyl bromide, which gave 7-chloro-3-ethylamino-2-(2-methylphenyl)imidazo[2,1-a]isoquinoline (Compound 159) as yellow needles and 7-chloro-3-diethylamino-2-(2-methylphenyl)imidazo[2,1-a]isoquinoline (Compound 199) as colorless needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06020342 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-06a647aba0e04f20b2b495becc18e101 |
| Source note | uspto-grants-2000_02 |