Hydrochloric Acid → HCID 15289736, compound

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Reaction Steps

To a solution of 300 mg (0,767 mmole) of the title product of Example 39 in 5 ml methanol is added 5 ml of 1M aqueous sodium hydroxide. After stirring at room temperature, the mixture is acidified with dilute aqueous hydrochloric acid and extracted with diethyl ether. The organic layer is dried over sodium sulfate, filtered, and evaporated. Chromatography of the residue over silica gel using mixtures of ethyl acetate, hexane, and acetic acid as eluents gives the title compound.

Provenance & Evidence