Ethanol → HCID 53693148, compound

Participants

Reaction Steps

0.1 g (0.2 mmol) of the ester from Example 77 were stirred overnight at room temperature in a mixture 2.5 ml ethanol and 0.35 ml 2 N aqueous sodium hydroxide solution. The reaction mixture was cooled with ice and brought to pH 5.5 with 2 N acetic acid. The precipitate of the title acid was filtered with suction, washed with a small amount of cold water, and dried at 50° C. in vacuo. Yield: 42 mg (59%) of beige crystals, m.p. 175-178° C.

Provenance & Evidence