1,4-Dibromo-2,5-bis(hexyloxy)benzene → HCID 19362111, compound

Participants

Reaction Conditions

Reaction Steps

Under N2 and at -78° C., n-BuLi (23.8 mL, 2.5M in hexanes) was added, over 30 min, to a solution of 1,4-dihexyloxy-2,5-dibromobenzene (25.92 g., 59.45 mmol) in THF (150 mL). After the addition, the reaction mixture was stirred at -78° C. for 1 h and was then quenched with aq. NH4Cl at -78° C. After the usual workup, 1,4-dihexyloxy-2-bromobenzene was obtained as a pale yellow liquid (97% yield).

Provenance & Evidence