N,N-dimethylformamide methanol → HCID 18982037, compound

Participants

Reaction Steps

3-Dipropylamino-5-hydroxybenzothiopyran (EP 0222 996; 620 mg, 1.6 mmol) was dissolved in 11 mL of dimethylformamide/methanol (6:2) and the solution was degassed (10mm, 22° C., 15 min). Pd(OAc)2 (11 mg) 1,3-bis-diphenyl-phosphinopropane (19 mg), and triethylamine (0.48 mL, 0.35 g) were added to the reaction mixture.

Provenance & Evidence