Potassium Carbonate → HCID 10642392, compound

Participants

Reaction Steps

1.5 g of 4-chloro-N-diaminomethylene-3-methylsulfonyl-6-ethyibenzamide [obtainable by reacting guanidine with 3-methylsulfonyl-4-chloro-6-ethyl-benzoic acid], 10 ml of 3-trimethylsilyloxypyridine and 2.9 g of K2CO3 are stirred, at 140° for three hours, in small sealed flasks. After cooling, the solid residue is separated off, washed with a little diethyl ether and dissolved in 50 ml of water. After the customary working-up, N-diaminomethylene-3-methylsulfonyl-6-ethyl-4-(3-pyridyloxy)benzamide is obtained, m.p. 219-223°.

Provenance & Evidence