HRID376895

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID712

Formaldehyde

CH2O

HCID70003

6,7,8,9-Tetrahydro-5H-benzocyclohepten-5-one

C11H12O

HCID18326499

N-Methylprop-2-en-1-amine--hydrogen chloride (1/1)

C4H10ClN

PRODUCTS

生成物

HCID19360508

未命名化合物

收率 86.1%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

5.2 g 6,7,8,9-tetrahydro-benzocyclohepten-5-one, 0.96 g paraformaldehyde and 10.0 g allyl-methylamine hydrochloride in 60 ml glacial acetic acid were reacted as in example 1, step 1. After analogous work-up, 6.7 g (84.8% of theoretical) 6-[(allyl-methyl-amino)-methyl]-6,7,8,9-tetrahydro-benzocyclohepten-5-one were obtained as a yellowish oil.