HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 18320523, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 18320538 | HCID 18320538 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 18320523 | HCID 18320523 | — |
Reaction Steps
Trifluoroacetamide enol ether 31 is hydrolyzed at 60° C. with finely ground K2CO2 (3 eq) in MeOH containing trace water. Work up by partitioning the mixture with EtOAc/H2O, followed by silica gel chromatography provides enol ether aniline 32.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06022964 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-6ec7492178204d8fb9fe560e2970b859 |
| Source note | uspto-grants-2000_02 |