HRID37712

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7723

4-Chlorobenzyl chloride

C7H6Cl2

结构：CCOC(=O)Cc1c(C)[nH]c2ccc(OCc3nc4ccccc4s3)cc12

HCID15288024

未命名化合物

PRODUCTS

生成物

结构：Cc1c(CC(=O)O)c2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Cl)cc1

HCID15288025

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

The title compound is prepared according to the method of Example 16 using 2-methyl-5-(2-benzothiazolylmethoxy)-1H-indole-3-acetic acid ethyl ester and 4chlorobenzyl chloride; however, the hydrolysis is carried out in aqueous methanol. Recrystallization from acetonitrile affords white crystals, m.p. 175°-176° C.

WORKUP

后处理

customRecrystallization from acetonitrile
customaffords white crystals, m.p. 175°-176° C.