Cyclohexanol → HCID 10920762, compound

HRID 377152Notes

Reaction equation

HRID 377152 reaction equation
C1(O)CCCCC1.[CH2:8]([C@@H:10]1[CH2:15][C:14]([CH3:17])([CH3:16])[CH2:13][CH2:12][C:11]1=[O:18])[CH3:9]>>[CH2:8]([C@@H:10]1[CH2:15][C:14]([CH3:17])([CH3:16])[CH2:13][CH2:12][C@H:11]1[OH:18])[CH3:9]

Participants

3

Reactant 2

HCID 7966CyclohexanolHCID 53960409(2R)-2-Ethyl-4,4-dimethylcyclohexanone

Product 1

HCID 10920762HCID 10920762, compound

Procedure

By proceeding as described above for the oxidation of its enantiomer, the above cyclohexanol (1.56 g, 10.0 mmol) was oxidized to (-)-(2R)-2-ethyl-4,4-dimethyl-1-cyclohexanone (1.36 g, 88%, 97% e.e. determined under the conditions described above).

Sources & evidence

ORD record
ord-92f483a79a324454a1a7d6de8d16f389
Source dataset
uspto-grants-2000_02
Patent number
US06025323

Reaction notes

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