Chloroform → HCID 54182173, compound

Participants

Reaction Steps

1.1 g of (R)-(-)-5-(3-benzyloxy-4-methoxyphenyl)-5-methyl-2-oxazolidinone is dissolved in 40 ml of ethyl acetate and mixed with 100 mg of palladium/10% carbon. It is hydrogenated until hydrogen absorption is completed. After filtration on silica gel and concentration by evaporation in a vacuum, 750 mg of (R)-(-)-5-(3-hydroxy-4-methoxyphenyl)-5-methyl-2-oxazolidinone, melting point 141.6° C., is obtained. [α]D =-28.2° (CHCl3).

Provenance & Evidence