HCID 10757880, compound → HCID 10825226, compound

Participants

Reaction Steps

Prepared from (S)-4-(3-iodo-4-aminobenzyl)-1,3-oxazolidin-2-one and 1,4-bis-triethylsilyl-3-butyn-1-ol as described for Intermediate 2, δ (360 MHz, D6 -DMSO) 2.74-2.91 (4H, m, 2 of CH2), 3.64 (2H, t, J=7.3Hz, CH2), 4.00-4.08 (2H, m, CH2), 4.20-4.26 (1H, m, CH), 6.92 (1H, dd, J=1.4 and 8.2Hz. Ar--H), 7.10 (1H, s, Ar--H), 7.25 (1H, d, J=8.2Hz, Ar--H), 7.36(1H, s, Ar--H), 7.75 (1H, s, NH), 10.69 (1H, s. NH).

Provenance & Evidence