HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azobisisobutyronitrile → tert-Butyl 2-(4-(bromomethyl)phenyl)-2-cyclopentylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Tert-butyl 2-cyclopentyl-2-(4-methylphenyl)acetate | HCID 15234721 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | tert-Butyl 2-(4-(bromomethyl)phenyl)-2-cyclopentylacetate | HCID 15225592 | — |
Reaction Conditions
| Temperature | 0 °C |
|---|
Reaction Steps
27.4 g (0.1 mol) of the compound from Example II are dissolved in 200 ml of carbon tetrachloride and the solution is heated to the boiling point. After addition of 0.82 g of azobisisobutyronitrile, 18.7 g (0.105 mol) of N-bromosuccinimide are added in portions, the mixture is then refluxed for 1 hour and cooled to 0° C. and the succinimide is filtered off. After concentration of the filtrate, the product precipitates out. It is washed with petroleum ether (40/60) and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06025378 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-e52497ed57324e21b53db14407db7dc8 |
| Source note | uspto-grants-2000_02 |