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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377258Generated: October 30, 2026

2-Chloro-N,N-dimethylethylamine → 1-(2-trifluoromethylbenzyl)-2-(3-methylphenyl)-6-[2-(N,N-dimethylamino)ethoxy]benzimidazole

https://huagongshe.com/reaction/377258

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-N,N-dimethylethylamineHCID 7901—
Reactant1-(2-Trifluoromethylbenzyl)-2-(3-methylphenyl)-6-hydroxybenzimidazoleHCID 19353988—
Product1-(2-trifluoromethylbenzyl)-2-(3-methylphenyl)-6-[2-(N,N-dimethylamino)ethoxy]benzimidazoleHCID 19354009—

Reaction Steps

The title compound was prepared essentially as described in Example 107 except that the compound of Example 120 was reacted with 2-(N,N-dimethylamino)ethyl chloride. mp 93° C., NMR, IR, MS 453.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06025379
Source datasetuspto-grants-2000_02
ORD IDord-867981f484d84f6e940a5cc5d7686dc9
Source noteuspto-grants-2000_02