HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-N,N-dimethyl-1-propanamine → 1-(2-trifluoromethylbenzyl)-2-(3-methylphenyl)-6-[3-(N,N-dimethylamino)propoxy]benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-N,N-dimethyl-1-propanamine | HCID 66960 | — |
| Reactant | 1-(2-Trifluoromethylbenzyl)-2-(3-methylphenyl)-6-hydroxybenzimidazole | HCID 19353988 | — |
| Product | 1-(2-trifluoromethylbenzyl)-2-(3-methylphenyl)-6-[3-(N,N-dimethylamino)propoxy]benzimidazole | HCID 19353991 | — |
Reaction Steps
The title compound was prepared essentially as described in Example 106 except that the compound of Example 120 was reacted with 3-(N,N-dimethylamino)propyl chloride. mp 74° C., NMR, IR, MS 468.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06025379 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-aa9e8233dedf40f9966dd0a8720e045d |
| Source note | uspto-grants-2000_02 |