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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377261Generated: October 28, 2026

2-Chloropropyldimethylamine → 1-(2-trifluoromethylbenzyl)-2-(3-methylphenyl)-6-[1-methyl-2-(N,N-dimethylamino)ethoxy]-benzimidazole

https://huagongshe.com/reaction/377261

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloropropyldimethylamineHCID 92738—
Reactant1-(2-Trifluoromethylbenzyl)-2-(3-methylphenyl)-6-hydroxybenzimidazoleHCID 19353988—
Product1-(2-trifluoromethylbenzyl)-2-(3-methylphenyl)-6-[1-methyl-2-(N,N-dimethylamino)ethoxy]-benzimidazoleHCID 19353944—

Reaction Steps

The title compound was prepared essentially as described above except that the compound of Example 120 was reacted with 1-methyl-2-(N,N-dimethylamino)ethyl chloride, yielding the title product as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06025379
Source datasetuspto-grants-2000_02
ORD IDord-6f8c0514ea0148349f8af8a01f5e9729
Source noteuspto-grants-2000_02