Methanol → 1-Phenethylamine

Participants

Reaction Steps

To a n-hexane and ethyl acetate solution (80 ml, 1:1) of the crude carboxylic acid was added (+)-1-phenylethylamine (1.96 g) with stirring at the room temperature. A precipitated colorless powder (3.97 g, mp : 125-131° C.) was collected by filtration and the additional powder (0.20 g, mp : 127-129° C.) was obtained from the filtrate Recrystallization of the combined powder from n-hexane--ethyl acetate (1:1, 100 ml) afforded a pure salt of (-)-5(S)-(3-methoxybenzyl)-1-cyclopentenecarboxylic acid and (+)-1-phenylethylamine as a colorless needles (3.27 g, mp : 135-136° C., [α]D : -21.87° (C=1, MeOH)).

Provenance & Evidence