Boron Trichloride → Diosmetin

HRID 377353Notes

Reaction equation

HRID 377353 reaction equation
C(OC1C=C(C=CC=1C)C1OC2C(C(=O)C=1)=C(C)C=C(OCC1C=CC=CC=1)C=2)C1C=CC=CC=1.[OH:36][C:37]1[CH:38]=[C:39]([CH:53]=[CH:54][C:55]=1[O:56][CH3:57])[C:40]1[O:41][C:42]2[C:47]([C:48](=[O:50])[CH:49]=1)=[C:46]([OH:51])[CH:45]=[C:44]([OH:52])[CH:43]=2.B(Cl)(Cl)Cl>C(Cl)Cl>[OH:36][C:37]1[CH:38]=[C:39]([CH:53]=[CH:54][C:55]=1[O:56][CH3:57])[C:40]1[O:41][C:42]2[C:47]([C:48](=[O:50])[CH:49]=1)=[C:46]([OH:51])[CH:45]=[C:44]([OH:52])[CH:43]=2

Participants

4

Reactant 2

HCID 25135Boron TrichlorideHCID 86755123HCID 86755123, compound

Product 1

HCID 5281612Diosmetin

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Preparation of 3',5,7-trihydroxy-4'-methoxy flavone 3',7-dibenzyloxy-4',5-dimethyl flavone(400 mg, 0.81 mmol) was dissolved in 12 mL of methylenechloride, and 1M of boron trichloride(2.7 mL) was added hereto at temperature of 0~5° C. Then the reaction mixture was stirred for 40 minutes.

Sources & evidence

ORD record
ord-d646ff3c30ab465484198427496364b8
Source dataset
uspto-grants-2000_02
Patent number
US06025387

Reaction notes

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