HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 86755128, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | HCID 6479252 | HCID 6479252 | — |
| Reactant | Ethylacetate heptane | HCID 21899848 | — |
| Product | HCID 86755128 | HCID 86755128 | 66.6% |
Reaction Steps
A suspension of methyl 2-methoxy-2-triphenylphosphonium acetate (2.22 g, 5.0 mmol) and DBU (750 mg, 5.0 mmol) in CH2Cl2 (20 ml) was stirred at RT for 15 minutes. Then (2E)-3-(quinolin-2-yl)-propenal (460 mg, 2.51 mmol) was added and the reaction conducted as seen for example 1. After a chromatography on silicagel (n-heptane/EtOAc 4/1) pure title compound was obtained (450 mg, 1.67 mmol, yield 66.6%) as brown crystals, m.p.=88°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06025390 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-165cd2eace9648348de9b6795c5eec39 |
| Source note | uspto-grants-2000_02 |