1-Methylimidazole → HCID 178464385, compound

Participants

Reaction Steps

4.0 g (60 mmol) of N-methylimidazole are added to 7.7 g (50 mmol) of 2-ethylaminoethyl chloride hydrochloride in 50 ml of absolute ethanol and the mixture is stirred for 36 hours at not more than 40° C. If higher temperatures are used, elimination takes place and the 1-methylimidazolium chloride thus formed can be removed only with difficulty. After the reaction is complete, the solution is concentrated under reduced pressure and the product is precipitated with ether. Washing a number of times with THF gives the product as a white hygroscopic powder. Yield: 9.3 g (83%).

Provenance & Evidence