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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377446Generated: October 25, 2026

2-Chlorobenzaldehyde → methyl 1-(2-chlorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate

https://huagongshe.com/reaction/377446

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorobenzaldehydeHCID 6996—
ReactantL-Tryptophan, methyl esterHCID 77980—
Productmethyl 1-(2-chlorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylateHCID 541453—

Reaction Steps

The same method but starting from racemic tryptophan methyl ester and 2-chlorobenzaldehyde gave the title compound as white crystals m.p.: 154° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06025494
Source datasetuspto-grants-2000_02
ORD IDord-8afe72f8ec8a4e8ba39ca422fc04a433
Source noteuspto-grants-2000_02