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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377453Generated: November 3, 2026

Piperonal → Methyl (1R,3S)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylate

https://huagongshe.com/reaction/377453

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperonalHCID 8438—
ReactantL-Tryptophan, methyl esterHCID 77980—
ProductMethyl (1R,3S)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylateHCID 9902999—

Reaction Steps

The same method but starting from L-tryptophan methyl ester and piperonal gave the cis and trans isomers of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06025494
Source datasetuspto-grants-2000_02
ORD IDord-3f59fba52b224816978f0db333a140d6
Source noteuspto-grants-2000_02