化工社化工社 化学情報印刷レポート · 研究参考用
4-Methoxybenzaldehyde → 8(p-Methoxyphenyl)-7-octennitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methoxybenzaldehyde | HCID 31244 | — |
| 反応物 | 6-Cyanohexyltriphenylphosphonium bromide | HCID 18795089 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 8(p-Methoxyphenyl)-7-octennitrile | HCID 53768714 | 71.1% |
反応手順
This compound was synthesized from 6-cyanohexyltriphenylphosphonium bromide (9.05 g, 20 mmol) and p-anisaldehyde (2.72 g, 20 mmol) in THF (100 mL) by a Wittig reaction. Kugelrohr distillation afforded the products (3.26 g, 71%) as a colorless liquid (bp: 143-146° C./0.05 torr). IR: 2285 cm-1 ; 1H-NMR: 1.50 (m, 6H), 2.30 (m, 4H), 3.80 (s, 3H), 5.50 (m, 1H), 6.30 (d, 1H), 7.05 (q, 4H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06025511 |
| 出典データセット | uspto-grants-2000_02 |
| ORD ID | ord-90b7046a429f40c5902476ebbff9ae9d |
| 出典メモ | uspto-grants-2000_02 |