反应详情

Compound 6e was prepared following the procedure described for 6b with reagent quantities adapted to the amount of starting material 5e (500 mg, 1.02 mmol). Yield: 305 mg, 0.60 mmol, 59%. 1H NMR (D2O): δ 7.72 (d, 3J=8.2 Hz, 2H, ArH), 7.52 (d, 3J=8.8 Hz, 2H, ArH), 7.03 (d, 3J=8.8 Hz, 2H, ArH), 4.01 (s, 4H, CH2COOH). ESI-MS calcd for C16H15IN2O7S 505.97 [M-H]−, obsd 507.0.