2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 11099874, compound

Participants

Reaction Steps

A solution of 2.6 g (8 mmol) of 1-(ethoxycarbonyl)amino-3,4-dihydro-4-methyl-6-(3'-trifluoromethylphenyl)-2-(1H)-pyridone in 75 ml of toluene is treated with 2.3 g (10 mmol) of DDQ and the mixture is refluxed for 6 hours. After cooling, the reaction solution is filtered off by suction through Alox n and the filtrated is evaporated on a rotary evaporator. The oil which remains is purified by column chromatography on Alox n (eluent: ethyl acetate:methanol=95:5).

Provenance & Evidence