Hydroxyamine hydrochloride → HCID 86755150, compound

Participants

Reaction Steps

Hydroxylamine hydrochloride (0.31 g) followed by sodium acetate (0.37 g) was added to a stirred solution of N-(3,5-dichlorophenyl)-2-(6-formyl-2,3-dihydro-4-oxo-5-phenyl-4H-1,3-oxazin-3-yl)-2-methylpropanamide (1.5 g) in ethanol at room temperature. After 10 minutes the precipitated solid was filtered, washed with ethanol and water, and dried to give N-(3,5-dichlorophenyl)-2-(2,3-dihydro-6-hydroxyiminomethylene-4-oxo-5-phenyl-4H-1,3-oxazin-3-yl)-2-methylpropanamide (compound 115, 0.53 g) m.p. 207.5-209.5° C.

Provenance & Evidence