Thionyl Chloride → HCID 19356159, compound

HRID 377604Notes

Reaction equation

HRID 377604 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[CH:21]=[CH:20][CH:19]=[CH:18][C:6]=1[O:7][C:8]1[CH:9]=[C:10]([CH2:14][C:15](O)=[O:16])[CH:11]=[CH:12][CH:13]=1)[CH3:3].S(Cl)([Cl:24])=O>>[CH3:1][N:2]([CH2:4][C:5]1[CH:21]=[CH:20][CH:19]=[CH:18][C:6]=1[O:7][C:8]1[CH:9]=[C:10]([CH2:14][C:15]([Cl:24])=[O:16])[CH:11]=[CH:12][CH:13]=1)[CH3:3]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 19356163HCID 19356163, compound

Product 1

HCID 19356159HCID 19356159, compound

Procedure

2 g of 3-(2-dimethylaminomethylphenoxy)-phenylacetic acid are treated with 20 ml of thionyl chloride and heated with stirring and under reflux for 1/2 an hour. The solvent is then removed. The residue is taken up with toluene and the solvent is again distilled off.

Workup

  1. temperatureheated
  2. temperatureunder reflux for 1/2 an hour
  3. customThe solvent is then removed
  4. distillationthe solvent is again distilled off

Sources & evidence

ORD record
ord-e62bde8b98164badaa054c55c7b4250b
Source dataset
uspto-grants-2000_02
Patent number
US06028080

Reaction notes

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