Thionyl Chloride → HCID 54505024, compound

HRID 377606Notes

Reaction equation

HRID 377606 reaction equation
[CH3:1][N:2]([CH:4]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:5]1[CH:6]=[C:7]([CH2:11][C:12](O)=[O:13])[CH:8]=[CH:9][CH:10]=1)[CH3:3].S(Cl)([Cl:23])=O>>[CH3:1][N:2]([CH:4]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:5]1[CH:6]=[C:7]([CH2:11][C:12]([Cl:23])=[O:13])[CH:8]=[CH:9][CH:10]=1)[CH3:3]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 54552481HCID 54552481, compound

Product 1

HCID 54505024HCID 54505024, compound

Procedure

1.5 g of 3-(dimethylaminophenylmethyl)phenylacetic acid are heated at reflux temperature for 1/2 an hour in 15 ml of thionyl chloride with stirring. Thionyl chloride not consumed in the reaction is distilled off. The residue is taken up in toluene and the solvent is distilled again.

Workup

  1. customThionyl chloride not consumed in the reaction
  2. distillationis distilled off
  3. distillationthe solvent is distilled again

Sources & evidence

ORD record
ord-772da762dd0f4cfa87e520001f2b56a7
Source dataset
uspto-grants-2000_02
Patent number
US06028080

Reaction notes

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