Phenyl N-(5,6-dimethyl-2-methoxypyridin-3-yl)carbamate → 1-[(5,6-Dimethyl-2-methoxypyridin-3-yl)aminocarbonyl]-4-(2-isopropenylphenyl)piperazine

HRID 377819Notes

Reaction equation

HRID 377819 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([NH:11][C:12](=[O:20])OC2C=CC=CC=2)[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8].[C:21]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[N:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1)([CH3:23])=[CH2:22]>>[CH3:1][C:2]1[CH:3]=[C:4]([NH:11][C:12]([N:33]2[CH2:34][CH2:35][N:30]([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=3[C:21]([CH3:23])=[CH2:22])[CH2:31][CH2:32]2)=[O:20])[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 11086894Phenyl N-(5,6-dimethyl-2-methoxypyridin-3-yl)carbamateHCID 19357124HCID 19357124, compound

Product 1

HCID 193571221-[(5,6-Dimethyl-2-methoxypyridin-3-yl)aminocarbonyl]-4-(2-isopropenylphenyl)piperazineYield 62%

Procedure

Phenyl N-(5,6-dimethyl-2-methoxypyridin-3-yl)carbamate and 1-(2-isopropenylphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-f1020634d7c746da811889a736f8a2ad
Source dataset
uspto-grants-2000_02
Patent number
US06028195

Reaction notes

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